Estradot (estradiol patches) — UK price comparison

Compare Estradot treatment services

All providers listed are GPhC-registered pharmacies or their linked online prescribing services. Prices are the pharmacy's own current service prices — where we haven't verified a price, check it on the pharmacy's site. Ordering is always subject to the pharmacy's own consultation.

Pick My Pharmacy is an independent comparison service and not a pharmacy. Where a listing is a referral partner we may earn a commission when you visit them — this never changes prices you pay, ratings, or the order providers appear. Affiliate links use rel="sponsored" and are labelled “Ad – Affiliate”. For Prescription Only Medicines we promote the pharmacy’s clinical service, not a specific medicine, in line with the MHRA Blue Guide. See our affiliate compliance.

What the price covers

UK online pharmacies price Estradot as a treatment service: the monthly figure normally includes the online consultation, review by a prescriber, the patches themselves, and tracked delivery. Always confirm what's included, because a pharmacy that looks cheaper may charge separately for consultations or delivery. Estradot is changed twice a week and comes in several strengths (from 25 micrograms up to 100 micrograms); the strength your prescriber sets can affect the pack price at some pharmacies, so compare at the strength you'll actually be using rather than the lowest advertised figure.

NHS or private — the honest comparison

Estradot is prescribed on the NHS, and for most people the NHS route is far cheaper than any private online pharmacy. In England, HRT medicines including estradiol patches are covered by the HRT prepayment certificate, which costs £19.80 and covers 12 months of HRT prescriptions — usually less than a single month of private supply. Prescriptions are free in Scotland, Wales, and Northern Ireland. The private route makes sense mainly for speed and convenience, or as a stopgap while waiting for a GP appointment — not as a way to save money. If you may qualify for NHS treatment, speak to your GP first.

What Estradot is and who it's for

Estradot is a transdermal patch that delivers estradiol — the oestrogen component of hormone replacement therapy — through the skin, changed twice weekly. Delivering oestrogen through the skin means it enters the bloodstream without first passing through the liver, which is a factual difference in delivery route between patches and tablets, not a claim that one is better: which form and dose suit you is a decision for your prescriber or GP. Anyone with a womb using oestrogen also needs a progestogen to protect the womb lining — again a prescriber decision, often prescribed alongside as a separate medicine such as micronised progesterone. Every legitimate pharmacy runs a structured consultation before supply and will decline where treatment isn't suitable.

Supply, safety and side effects

HRT patches, including estradiol patches, have seen intermittent UK supply issues in recent years, so it is worth checking availability with the pharmacy — or your GP surgery — before relying on a delivery date, whichever route you use. Common side effects include skin irritation at the patch site, breast tenderness, and headaches; the prescriber consultation screens for anything that would make oestrogen unsuitable. Buy only from GPhC-registered pharmacies, report suspected side effects through the MHRA Yellow Card scheme, and speak to the pharmacy's clinical team or your GP if you're unwell. This page compares prices only — it is not medical advice.

Frequently Asked Questions

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Related Pages

• Is an online pharmacy legit? How to check
• Online pharmacy UK guide
• HRT prepayment certificate calculator
• What is a prescription prepayment certificate?